The University of Pisa is a public institution, officially established in 1343. With 20 departments and high-level research centers in multiple areas.
In DAEDALUS, this institution is represented by the Biofabrication Group of the Research Center “E. Piaggio” of the University, one of the oldest interdisciplinary research and technology transfer centers in Europe. Since its foundation in September 1965, the Center “E. Piaggio” has paved the way for the convergence of minds by bringing together scientists from different fields of knowledge, with bioengineering and robotics as main research topics.
Role in DAEDALUS:
UNIPI is the coordinator of the DAEDALUS project and leads the development of a multifunctional endoscopic tool for precise in-body delivery of biomaterials. The team also designs intestinal models to test the biomaterials and applies AI-assisted tools to support the design and optimization of smart, responsive 4D composites.
Politecnico di Torino was the first Italian Engineering School founded in the wave of the technical and scientific innovation that gave rise to the most prestigious European polytechnic schools in the mid-19th century.
Founded as School for Engineers in 1859, it then became Regio Politecnico di Torino in 1906. Engineers, architects, designers and urban planners have been trained at Politecnico di Torino for over 160 years.
WURZ Universitätsklinikum Würzburg was founded more than 400 years ago and it’s one of the oldest – and modern – teaching hospital in german speaking Countries. It counts 19 clinics, 3 autonomous polyclinics and 4 clinical institutes that offer high-quality medical care and conducts cutting-edge research. Every year the Hospital accommodates more than 330.000 inpatients and outpatients.
Close cooperation with the Medical Faculty of the University of Würzburg and other research institutions enables the provision of innovative treatments in numerous fields.
The hospital is ranked as one of the best in Germany attracting patients and professionals from all over the world.
Role in DAEDALUS:
UKW contributes to the development of advanced biomaterial scaffolds and support structures. It focuses on tailoring the physical and chemical properties of materials and on integrating them into the complete endoscopic system, while supporting in vitro testing and scale-up activities.
Founded in 1404, the University of Turin (UniTo) is a public institution of High Education. UNITO boasts the largest Department of Surgical Sciences in Italy. The faculty staff has the leading positions in the international arena of scientific research especially on minimally invasive therapy, robotics, clinical imaging and interventional radiology and innovative materials for surgical applications.
Role in DAEDALUS:
UNITO provides clinical expertise to guide the selection and testing of materials and tools. Surgeons from UNITO are involved in preclinical validation of the DAEDALUS solution, using realistic anatomical models and performing tests in ex vivo and in vivo settings.
IBMM (University of Montpellier, CNRS, ENSCM) is one major French institute of research recognised for its work in the different classes of essential biomolecules: lipids, sugars, nucleosides and oligonucleotides, peptides and proteins, prebiotic molecules and biopolymers. IBMM displays its skills for integrated research, with the aim of understanding the mechanisms of life by designing molecules and systems useful for biology, medicine, and agriculture while developing green chemistry processes.
Within IBMM, The Department of Polymers for Health and Biomaterials (PHBM) is a multidisciplinary research group dedicated to polymers related to biomedical applications. The PHBM researches focus on designing, synthesizing, characterizing and evaluating polymers to meet the requirements of therapeutic applications. The PHBM is recognized for its expertise in degradable polymers and polymer biomaterials for healthcare applications and gathers experts in polymers, macromolecular chemistry and biomedical sciences.
Role in DAEDALUS:
The PHBM team develops innovative degradable polymers tailored for biomedical applications.
Inaugurated in 1817, counts several Nobel Prize winners between its alumni and it’s the first European University in South Korea.
The IBD Research Unit is expert in model systems (in vitro, ex vivo, organ on a chip, mouse models) to study the inflamed bowel, translational medicine and initiating academic clinic trials, biobank, gut fibrosis and gut-brain communication.
Role in DAEDALUS:
UGent combines its expertise in polymer chemistry and gastrointestinal research. The team synthesizes light-responsive hydrogels and performs comprehensive preclinical testing, including in vitro and animal models, to validate the therapeutic potential of the 4D materials.
AdBioInk is a pioneering high-tech company specializing in the production of advanced biomaterials, especially bioinks, biopolymers and extracellular matrix (ECM) and was the first company to introduce the BioPen, a portable bioprinter system. AdBioInk is committed to providing innovative, easily accessible, and high-quality biomaterials.
Role in DAEDALUS:
AdBioInk adapts its portable BioPen-X bioprinting device for use in endoscopic procedures. Their work focuses on enabling the precise in situ delivery of multiple biomaterials, helping to recreate complex tissue structures inside the body with minimal invasiveness.
THIOM is a research center situated in Innsbruck. Founded in 2003, ThioMatrix currently counts 10 to 15 employees. The center is specialized on the development of non-invasive drug delivery systems utilizing its core technologies: Thiomer Technology and SEDDS Technology.
Role in DAEDALUS:
ThioMatrix brings its expertise in advanced drug delivery systems to support the formulation of smart therapeutic components in the DAEDALUS biomaterials. The team also leads the project’s regulatory strategy and contributes to scaling up production of materials from lab to preclinical stages.
Role in DAEDALUS:
AIJU leads efforts to ensure the social acceptability and patient engagement aspects of DAEDALUS. The team conducts studies with citizens and end-users, develops educational materials, and supports activities aimed at increasing awareness and acceptance of the new therapy approach.
BEWH is the Belgium branch of the Italian company Tinexta Innovation Hub, a privately held consultancy services company that provides full-spectrum consulting in business finance. BEWH has extensive experience in project management, communication, dissemination, and exploitation of project results, as well as environmental, economic, and social impact assessment. BEWH offers a methodological and strategic approach for the successful implementation of EU-funded research and innovation projects.
Role in DAEDALUS:
BEWH is responsible for the project’s communication, dissemination, and exploitation strategy. It ensures that project results reach the right stakeholders, coordinates networking activities, and supports the management of data, training actions, and impact tracking.
Role in DAEDALUS:
Role in DAEDALUS:
Role in DAEDALUS: